250+ TOP MCQs on Infection Process – Penetration of Epithelial Cell Layers and Answers

Microbiology Multiple Choice Questions on “Infection Process – Penetration of Epithelial Cell Layers”.

1. Which of the following microorganism causes infection in burns?
A. Pseudomonas aeruginosa
B. Clostridium perfringens
C. Borrelia sp
D. Streptococcus sp
Answer: A
Clarification: Burns often become infected by Pseudomonas aeruginosa or other aerobic or facultatively anaerobic bacteria from the surrounding.

2. V. cholerae does not penetrate into the body.
A. True
B. False
Answer: A
Clarification: V. cholerae, the causative agent of cholera, multiplies on the epithelial layer of the small intestine where it produces a toxin that causes the loss of fluid from the epithelial cells and kills the cells.

3. Which of the following microorganism causes relapsing fever in humans?
A. Pseudomonas aeruginosa
B. Clostridium perfringens
C. Borrelia sp.
D. Streptococcus sp.
Answer: C
Clarification: Borrelia sp. cause relapsing fever in humans when the spirochetes are introduced through the bite of a tick or a body louse.

4. Which of the following microorganism participates in active penetration into the body?
A. Clostridium perfringens
B. Shigella
C. Borrelia sp.
D. Pseudomonas aeruginosa
Answer: B
Clarification: In bacillary dysentery, Shigella bacteria penetrate into and kill the epithelial cells of the colon, then spread to adjacent cells, which are in turn killed.

5. Wounds and burns represent one active mechanism.
A. True
B. False
Answer: B
Clarification: Wounds and burns represent one passive mechanism and they can introduce pathogens directly into the underlying tissues.

6. Bacillary dysentery is caused by which of the following microorganism?
A. Clostridium perfringens
B. Borrelia sp.
C. Shigella
D. Pseudomonas aeruginosa
Answer: C
Clarification: Bacillary dysentery is caused by Shigella bacteria which penetrate into and kill the epithelial cells of the colon, then spread to adjacent cells, which are in turn killed.

7. In which of the following body part does the influenza virus does not penetrate?
A. small intestine
B. nasopharynx
C. trachea
D. bronchi
Answer: A
Clarification: The influenza virus penetrates the epithelial cells lining the nasopharynx, trachea and bronchi.

8. Which of the following is an arthropod?
A. Clostridium perfringens
B. Borrelia sp.
C. Shigella
D. Pseudomonas aeruginosa
Answer: B
Clarification: Arthropods follow passive penetration such as that by Borrelia species which causes relapsing fever in humans.

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