[Biology Class Notes] on First Human Heart Transplant Pdf for EXAM

What is Heart Transplant?

Removal and replacement of a diseased heart with a healthy heart from an organ donor is called heart transplant. Heart transplant is a medical term and it is done by medical professionals where two or more healthcare providers must declare the donor brain as dead. It is also referred to as cardiac transplant and involves surgical procedure to replace the heart with severe coronary artery disease or end-stage heart failure condition when all other medical or surgical treatments are no more hope.

Some Facts Related to Heart Transplant

  • Every year, approx 3.5 K heart transplants are performed worldwide and over half of this is done in the US. 

  • It is known that the post-operative survival period for a patient is 15 years. 

  • Heart transplantation can be considered as a life-saving treatment rather than a cure for heart disease which aims to improve the duration and quality of life of the patient.

  • Before human-to-human transplant, earlier, the heart of a chimpanzee was transplanted into the chest of a human, Boyd Rush. However, due to this kidney failure in humans was observed. Later, we will discuss in detail about the first human heart transplant in this article. 

When Was the First Human Heart Transplant Operation Done?

The first human-to-human heart transplant was performed in the year 1967 on December 6. It was performed by South African cardiac surgeon named Christiaan Barnard on Louis Washkansky in Cape Town, South Africa. However, the patient died after 18  days of the operation due to pneumonia.

Further, in the 1970s, better anti-rejection drugs were discovered that made the heart transplant process more viable. Dr. Barnard was dedicated to perform heart transplantation and by the late 1970s, many of the recipients were able to live up to five years with the receiving of new hearts. Today, much of the successful heart transplant stories can be found and the only difficult part is to find appropriate donors.

 

Why Did Louis Washkansky Need a Heart Transplant?

Washkansky was a South African grocer suffering from chronic heart disease, and the first Louis Washkansky heart transplant was performed and was possible because of the recipient named Denise Darvall who was a 25-year-old woman and fatally injured in a car accident. Surgeon Christiaan Barnard was the person to perform it at the University of Cape Town.

 

First Pediatric Heart Transplant

It was performed on the 6th of December, 1967 in Brooklyn, New York at Maimonides hospital. It was performed by Adrian Kantrowitz, however, the infant’s new heart stopped functioning after 7 hours and thus the surgeon admitted that the operation was unsuccessful.

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