Industrial Pharmacy 1 Multiple Choice Questions
1. What is dip coating?
A. Repeated coating and drying
B. Application of protein two substances which can conduct charge
C. Air in coating pan is replaced by nitrogen
D. Acid insoluble coating
2. Magnesium stearate is used as
A. Anti – oxidant
B. Anti-adherent
C. Tablet Glidant
D. Film Coating
3. Which test microorganism is used for most heat sterilization technique?
A. Bacillus Subtilis
B. Bacillus Pumilus
C. Bacillus Thermophiles
D. Pseudomonas Demunita
4. What is Humectant?
A. It reduces the particle size of powder material
B. It is used to increase the thickness of appointment
C. It is used to prevent drying of the cream
D. It is used to increase spread of court over the tablet
5. In tablet defect picking means
A. Colouring distribution is not proper
B. Partial or complete removal of top or bottom of tablet
C. Adhesion of tablet material to sides of die
D. Two distinct layer on tablet
6. The role of borax in cold creams is
A. Anti-microbial agent
B. To provide fine particles to polish skin
C. In-situ emulsifier
D. Antioxidant
7. Three (03) size of capsule will have how much volume capacity?
A. 1.3
B. 0.95
C. 0.68
D. 0.30
8. Gelatin is used as
A. Encapsulating Agent
B. Antimicrobial agent
C. Viscosity Enhancing Agent
D. Tablet Glidant
9. All of the following are antioxidant agent except
A. Ascorbic acid
B. Propyl gallate
C. Sodium chloride
D. Both A &C
10. Sub-coating is given to tablets
A. To increase the bulk and to round-up the edge
B. To avoid the deterioration due to microbial attack
C. To prevent the solubility in acidic medium
D. To avoid stickiness
11. In nail polish, following polymer is used as a film-former:
A. Nitrocellulose
B. Polylactic acid
C. Hydroxypropyl methylcellulose
D. Cellulose acetate phthalate
12. Water for injection differs from sterile water for injection because it is free from
A. Carbon dioxide
B. Pyrogen
C. Preservative
D. Anti-Oxidant
13. Disposable syringe are made up of
A. Transparent Polyester
B. Polypropylene
C. Glass
D. PTFE
14. Bloom strength is used to check the quality of
A. Lactose
B. Ampoules
C. Hardness of tablets
D. Gelatin
15. The role of borax in cold creams is
A. Anti-microbial agent
B. To provide fine particles to polish skin
C. In-situ emulsifier
D. Antioxidant
16. Which one of the following drying methods is commonly used in pharma industry for drying of soft shell capsules?
A. Truck drying
B. Fluid bed drying
C. Vacuum drying
D. Microwave drying
17. Sweetening agent commonly used in chewable tablet formulas
A. Sucrose
B. Cyclamate sodium
C. Saccharin sodium
D. Mannitol
18. The following test are necessary for the quality testing of parenteral product except
A. Pyrogen test
B. Total organic content
C. Conductivity Test
D. All of Above
19. Which is also known as wurster Coater?
A. Pan coater
B. Fluid Bed Coater
C. Perforated Pan Coater
D. None of Above
20. Non uniformity during uneven colour distribution in tablet surface is called
A. Orange peel effect
B. Mottling
C. Pitting
D. Blistering
21. The purpose of seal coating in sugar coating process for tablet is
A. To prevent moisture penetration in to tablet core
B. To round the age and build up tablet weight
C. Impart the desired colour to the tablet
D. To give luster to the tablet
22. Durability of tablet to combined effect of shock and abrasion is evaluated by using
A. Hardness tester
B. Disintegration test apparatus
C. Friabilator
D. Screw Gauge
23. Which of the following defect is due to highly viscous coating solution?
A. Lamination
B. Orange peel
C. Cracking
D. Blushing
24. Moisture content of empty capsule shell should be between
A. 12-15
B. 5-83
C. 2-6
D. 20-25
25. Vanishing cream is an ointment that be classified as –
A. A water soluble base
B. An absorption base
C. An emulsion base
D. An oleic base
26. Which of the following is not act as plasticizer?
A. Propylene glycol
B. Polyethylene glycol
C. Polycarbonate
D. Tween
27. When given intravenously, a drug has bioavailability of –
A. 10 %
B. 50 %
C. 100 %
D. 75 %
28. Which is most recently used reagent for validation of HEPA filter?
A. Emory 3004
B. LAL Reagent
C. Alcohol
D. None
29. Space required for manufacturing parenteral product
A. 50 meter square
B. 60 meter square
C. 80 meter square
D. 100 meter square
30. Non parental type of glass consists of which of the following type
A. Type -I
B. Type -II
C. Type -III
D. Type -IV
31. A synthetic sweetening agent which is approximately 200 times sweeter than sucrose and has no after taste is?
A. Saccharin
B. Aspartame
C. Cyclometer
D. Sorbitol
32. As per GMP permitted limit of soluble content in water for injection is
A. 100 PPM
B. 0.1 PPM
C. 01 PPM
D. 10 PPM
33. Lal test stands for
A. Linker allele lyase
B. Limulus amoebocyte lysate
C. Lecithin antigen linkage
D. None
34. Which of the following is commonly used as a preservative in eye drops?
A. Propyl paraben
B. Butylated hydroxy Toluene
C. Phenol
D. Benzalkonium chloride
35. What is the dose of intra dermal injection?
A. 0.1-0.2ml
B. 2-4 ml
C. 1-2 ml
D. 5-10 ml
36. Which of the following are not parenteral androgens?
A. Testosterone
B. Testosterone propionate
C. Testosterone enanthate
D. Methyl testosterone
D. Transdermal patch
37. Which Surfactant is not used parenterally?
A. PEG
B. Tween
C. Povidone
D. Cetyl trimethyl ammonium bromide
38. Water for injection should not be held at room temperature for time period of.
A. 24 hour
B. 48 hours
C. 72 hours
D. 36 hours
39. Which of the following dye is used for the leakage test?
A. Orange Red
B. Methylene blue
C. Methylene red
D. None of above
40. Which of the below has minimum permissible solid content?
A. Water for injection
B. Distilled water
C. Bacteriostatic WFI
D. Sterile WFI
41. Which of the following doses form is suitable for how to get 100% bioavailability of drug?
A. Tablet
B. Capsule
C. IV injection
42. Water attack test is used to identify the alkalinity in
A. Type 1
B. Type 2
C. Type 3
D. All of the Above
43. Which of the following is a not physical characteristic of product?
A. Crystallinity
B. Osmolarity
C. Wettability
D. Partition coefficient
44. Value of angle of repose < 30 indicates?
A. Good flow property
B. Passable
C. Excellent flow property
D. Poor
45. Which of the following is not step of wet granulation?
A. Shifting
B. Granule formation
C. Drying
D. Compression
46. What is bolting of lubricant?
A. Lubricant is passed through 150 mesh of nylon cloth
B. Lubricant is passed through 100 mesh of nylon cloth
C. Lubricant is completely dried before use
D. Lubricant is mixed with excipients before reading
47. Which of the following is a carbohydrate based binder?
A. Gelatin
B. PVP
C. Both
D. None
48. Ratio of dry glycerin/dry gelatin for hard gelatin capsule is…..?
A. 0.6:1
B. 0.4:1
C. 0.8:1
D. 1:0.8
49. The chemical nature of Eudragit is similar to
A. Acrylic Acid
B. Methacrylate
C. Lactate -co glycoside
D. Methyl cellulose
50. Filling of liquid in capsule is done by
A. Roto fills
B. Roto sort
C. Accofill
D. Pelletofill
51. Tablet that is placed under the skin called as ….?
A. Electric coated tablet
B. Film coated tablet
C. Implant
D. Sublingual
52. Disintegration time for sugar coated tablet is….?
A. 30 min
B. 45 min
C. 60 min
D. 75 min
53. In the preparation of tablets are mixed for …?
A. To reduce the total volume
B. To increase adsorption
C. To increase adhesiveness
D. To reduce inter particulate friction
54. Ingredients used for the capsulation in soft gelatin capsules should flow by gravity at a temperature not exceeding
A. 35 ˚C
B. 25 ˚C
C. 20 ˚C
D. 30 ˚C
55. Bulking agent used for parenteral preparation is
A. Sodium metabisulfite
B. Benzyl alcohol
C. Carbolic acid
D. Sorbitol
56. The formula for the preparation of ascorbic acid injection IP may include
A. Glacial acetic acid
B. Dilute HCL
C. Propylene glycol
D. Sodium carbonate or sodium bicarbonate or sodium hydroxide in water
57. Limulus test is rapid in vitro test for parenteral to detect the presence of…?
A. Particulate matter
B. Fungus
C. Pyrogen
D. Bacteria
58. If the Carr’s index of to powder is 10% type of powder flow is…?
A. Poor
B. Excellent
C. Very Poor
D. Good
59. Before washing ampoules the mouth of each ampoule is rotated in Bunsen flame to melt down the rough edges. This process is called as…?
A. Flaming
B. Charging
C. Annealing
D. Grounding
60. Which of the following is not component of pharmaceutical aerosol?
A. Propellant
B. Container
C. Valve
D. Roll Tube
61. Which of the following is not large scale equipment for the manufacturing of pharmaceutical aerosols?
A. Concentrate filler
B. Valve pressure,
C. Pressure filler,
D. Cold Filler
62. What are the two principle ingredients of pharmaceutical Aerosol?
A. Active ingredient
B. Actuators
C. Propellant
D. Both A&C.
63. Pharmaceutical aerosols generally which type of dosage form
A. Stable dosage form
B. Highly unstable dosage form
C. Meta-stable dosage form
D. Unstable dosage form
64. Super-Disintegrants in tablet formulation is..?
A. Sodium starch glycolate
B. Starch
C. PVP
D. Mg-aluminum silicate
65. The propellant is responsible for to…?
A. Developing proper pressure within container
B. For provide actual shape of products for
C. Expels the product
D. Both A&C.
66. Among the following which is type of inhalational device
A. Metered dose inhaler
B. Nebulizer
C. Dry powder inhaler
D. All of them
67. Nebulizer is of how many types?
A. One
B. Two
C. Three
D. Four
68. The component of pharmaceutical aerosols which ensures that the product is delivered in proper and desired form is called….?
A. Propellant
B. Actuator
C. Valve
D. Dip tube
69. How many types of actuators?
A. 1
B. 2
C. 3
D. 4
70. Chilsonator is used as…
A. Tablet Coating
B. Capsule filling Machine
C. Tablet Granulator
D. None of Above
71. Temper evident packaging is the term originated by….
A. PCI
B. AICTE
C. FDA
D. CDL
72. The two primary components of blister packaging are …?
A. Cavity
B. Round edges
C. Liding
D. Both A& C
73. Which type of glass container is not generally used for parenteral preparation?
A. Type 1
B. Type 2
C. Type 3
D. Type 4
74. Type 2 glass is also known as….
A. Highly resistant borosilicate glass
B. Treated soda lime glass
C. Soda lime glass
D. General purpose soda lime glass
75. Pre – formulation studies mainly focus on
A. Physical properties of new compound
B. Chemical properties of new compound
C. Physico-chemical properties of new compound
D. None
76. Which of the following information is helpful in designing the pre formulation evaluation of a new drug?
A. Structure of a compound
B. Formula & molecular weight of a compound
C. Therapeutic indication of a new compound
D. All the above
77. Which of the following problems commonly encountered in evaluating salt forms are
A. Poor crystallinity
B. Hygroscopicity
C. Instability
D. All the above
78. Which of the following salts generally used in pharmaceutical products?
A. Acetate
B. Gluconate
C. Lactate
D. All the above
79. Description of the outer appearance of a crystal is known as….?
A. Crystal habit
B. Internal structure
C. Both
D. None internal structure
80. Amorphous forms generally having
A. Low thermodynamic energy & low solubility
B. High thermodynamic energy & high solubility
C. Both
D. None
81. Which of the following compound possess high aqueous solubility’s?
A. Hydrates
B. Anhydrates
C. Both
D. None
82. Which of the following properties may change with changing of the internal structure of a solid?
A. Melting point
B. Density
C. Optical properties
D. All the above
83. Which of the following methods generally used for studying solid forms?
A. DSC
B. XRD
C. TGA
D. All the above
84. Which of the following methods generally used to measure heat loss or gain within a sample?
A. DSC
B. DTA
C. Both
D. None
85. Department of Transport Test (DOT) is performed for which of the following?
A. Aerosols
B. Glass containers
C. Capsules
D. None
86. Measurement of particle size in pharmaceutical aerosol is by (P) Cascade impactor (Q) Light scatter decay (R) K-F method (S) IR
A. P, Q
B. Q, R
C. R, S
D. P, S Q, R
87. Identify the correct non-flammable propellant
A. Trichloro mono fluoromethane
B. Dichloromono fluoromethane
C. Di methyl ether
D. Difluoromethane
88. The dip tube in an aerosol container is made from one of the following
A. Polypropylene
B. Glass
C. Al
D. Stainless steel
89. Which one of the following device is used to increase the efficiency of drug delivery via aerosols?
A. Tube spacers
B. Metered valves
C. Actuator
D. Pressure valve
90. Department of Transport Test (DOT) is performed for which of the following?
A. Aerosols
B. Glass containers
C. Capsules
D. None
91. The first pharmaceutical aerosol was developed in year of,
A. 1945
B. 1955
C. 1949
D. 1960
92. Which drug is formulated is first pharmaceutical aerosol?
A. Epinephrine
B. Codeine
C. Chlorpromazine
D. Probenecid
93. Titanium Dioxide commonly present in
A. Vanishing Cream
B. Sun Screen cream
C. Opthalmic cream
D. Aqu. Calamine cream
94. Rotosort is a machine for short out….
A. Coated Tablet
B. Filled Capsule
C. Sealed ampoules
D. S.G. CAP
95. In sugar coating, seal coat is done.
A. To prevent moisture absorption
B. To round the edges and build up tablet
C. To prevent breaking of Tablet
D. To smoothen Tablet
96. Shellac is used for the purpose of coating of tablet is
A. Polishing Agent
B. Film Coating Agent
C. Enteric Coating
D. Sub coating
97. The agent which improve the flow property of granules
A. Anti-adherent
B. Glidant
C. Lubricant
D. Emollient
98. The propellant used for Topical Aerosols
A. Dicholoro difluro methane
B. Tricholoro mono fluromethane
C. Propane
99. Sterility test for surgical suture require incubation for
A. 14 Days
B. 7 Days
C. 21 Days
D. 28 Days
100. Sigma blade mixture commonly used in
A. Wet Granulation
B. Dry Granulation
C. Powder Mixing
D. Crude Fiber Mixing
101. Poorly mfged Tablets have small pinholes on the surface known as
A. Mottling
B. Picking
C. Cracking
D. Leaching
102. Which of the following preparation will be the most irritating
A. P. water
B. 0.9% NACL
C. 0.7% NACL
D. 1% NACL
103.Match the following Terms
(1) Zanasi A. Tab. Granules
(2) HEPA Filter B. Tab. Coating
(3) Chilsonator C. Injection
(4) Aceela cota D. Capsule
Ans. 1-D, 2-C, 3-A, 4-B
104. Ingredients used for capsulation in soft gelatin capsule should flow by gravity at a temperature not exceeding;
A. 35˚C
B. 30˚C
C. 25˚C
D. 20˚C
105. Green bone are used for the preparation of a gelatin of the type;
A. TYPE A
B. TYPE B
C. TYPE C
D. TYPE A& B Both
106. The moisture content of capsule shell is determined by;
A. Steam distillation Method
B. Fractional Distillation Method
C. Toluene Distillation Method
D. None of Above
107. In capsule, ROTOFILL is used for filling-
A. Powders
B. Pellets
C. Liquids
D. Corrosive Liquid
108. Generally, ”Gelatin” used in the manufacture of soft gelatin capsules contain Iron element;
A. 25 PPM
B. NMT 15 PPM
C. NMT 10 PPM
D. Between 10-15 PPM
109. Soft gelatin capsules are prepared by:
A. Plate Process
B. Rotary die Process
C. Reciprocating die Process
D. All of above
110. For weight variation test, according to USPXX, minimum capsules required is;
A. 10
B. 20
C. 30
D. 40
111. The crown thickness of individual tablets are measured with;
A. A Micrometer
B. A sliding caliper Scale
C. Both A& B
D. None of Above
112. In multi-station presses the portion holding the dies is called.
A. The die table
B. The turret
C. The cam-Tracks
D. None of Above
113. In multi-station rotary tablet press, the portion of which hold the upper and lower punches are called the,
A. Upper and lower turrets respectively
B. Upper and lower cam- tracks respectively
C. All of above
D. None of Above
114. The maximum amount of oil that can be added to a granulation as flavouring agent without affecting its tableting characteristics is;
A. 0.5 -1.0%
B. More than 0.7%
C. Between 0.5-0.7%
D. Between 0.1-0.25%
115. Pyrogen can be completely destroyed from parenteral container by:
A. Heating at 650˚F for 60 sec.
B. Heating at 650˚C for 60 sec.
C. Heating at 650˚C for 60 min
D. Heating at 210 ˚C for 60 min
116. For evaluating chemical resistance of glass, USP provides;
A. The Powdered glass test
B. The Water attack Test
C. Both A&B
D. None of above
117. USP Glass type –I Stand for:
A. Soda lime glass
B. Treated soda lime glass
C. Highly resistant borosilicate glass
D. General Purpose soda lime glass
118. Water attack test is generally used for,
A. USP TYPE I Glass
B. USP TYPE II Glass
C. USP TYPE I & III Glass
D. USP TYPE II & III Glass
119. Leaker Test is carried out for
A. Vials
B. Ampoules
C. Bottles
D. All of Above
120. A parenteral product must be;
A. Packed in Bottles
B. Sterilized
C. Free of living organism
(E) Pyrogenic
121. Oils used to make parenteral products must be
A. Good lubricant
B. Metabolizable
C. Good Solvent
D. Neutral Product
122. Water for Injection USP is prepared by
A. Distillation or Reverse Osmosis
B. Filteration
C. ION-Exchange Method
D. All of above
123. Parenteral solution containing relatively small amount of Insoluble impurities are best removed by
A. Cake Filter
B. Depth Filter
C. Screen Filter
D. All of Above
124. Sterile emulsion are mainly used for
A. I.V. Hyper alimentation
B. Dry Vehicle
C. Eye Drops
D. Treatment of allergies
125. Total Parenteral Nutrition (TPN) Solution Contains:
A. Lipids
B. Vitamins & Trace elements
C. Amino Acid
D. All of the Above
126. Ideally TPN Solutions are administered;
A. Orally
B. By peripheral Vein
C. Rectally
D. By indwelling central catheter
127. Efficiency of HEPA Filter can be checked by;
A. Leak Test
B. DOP Test
C. Pyrogen Testing
D. LAL Test
128. WFI differ from sterile distilled water as it is free from
A. CO2
B. Preservative
C. Pyrogen
D. Antioxidant
129. Porosity of Porous Powder is defined as
A. Bulk volume/Void volume
B. Void volume/Bulk volume
C. Void volume/True volume
D. True volume/Bulk volume
130. High AOR of granules indicates;
A. Bulk density of granules
B. Porosity of granules
C. Roughness of granule surface
131. On commercial scale emulsions are prepared by;
A. Centrifugation
B. Dialysis
C. Freezing
D. Homogenization
132. Type II glass is prepared from Type III glass by surface treatment with;
A. Lime
B. Oxygen
C. Sulfur dioxide
D. Silicon
133. The water resistance of glass container is tested by measuring;
A. Amount of acid released into water
B. Amount of alkali leached into water
C. Determination of Silicon Level
D. After Autoclaving turbidity of an aqueous solution
134. Aspirin USP tablets should be packed and stored in:
A. Well closed container
B. Tightly closed container
C. Light resistant container
D. Both B&C
135. The storage temperature of Aerosols should never exceed;
A. 37˚C
B. 120˚F
C. 100˚F
D. 120˚C
136. An Isotonic solution is one which;
A. Does not cause hemolysis
B. Has same salt composition
C. Does not cause crenulations
D. Has a freezing point less than that of plasma
137. Although isotonicity is desirable for almost all parenterals it is particularly critical for which Injection?
A. I.V.
B. I.M.
C. Intra-dermal
D. Subcutaneous
138.Carnauba wax is used in the following step of sugar coating of tablet:
A. Seal coating
B. Polishing
C. Sub-coating
D. Syrup coating
139.The volume of injection of IM route is;
A. 0.1ml to 2.0 ml
B. 10 to 50 ml
C. 0.2 to 0.4ml
D. 2.0 to 4.0 ml
140. Elastomer used in rubber stopper formulation is-
A. Polybutadene
B. Butyl stearate
C. Titanium dioxide
D. BHT
141. Orange peel defect in film coating of tablet means
A. Poor spreading of sprayed droplets of coating solution
B. Excessive coating process
C. Precipitation of polymer due to poor solvent
D. High internal stress in film
142. Cab-o-sil is generally used as:
A. A Flow promoters
B. A Binder
C. A Disintegrants
D. A super Disintegrant
143. One of the following is also known as sugar based diluent:
A. Nu Tab
B. Emdex
C. Celutab
D. Aerosil
144. The volume that can be injected intradermally is:
A. 0.1 to 0.2 ml
B. 2 to 4 ml
C. 1 ml or more
D. None of Above
145. The compression properties in Preformulation studies includes
A. Fragmentability
B. Elasticity
C. Punch filming properties
D. All of Above
146. Which of the following is appropriate with slugging?
A. Heat sensitive drugs
B. Moisture sensitive drugs
C. Direct compression
D. All of above
147. Oral tablets containing…. Substance most be dissolved in water before administration to avoid gastric irritation
A. Starch
B. Sodium Chloride
C. Stearic Acid
D. Sodium lauryl sulphate
148. Among the given lubricants, which is not used in oral tablets?
A. Hydrogenated Vegetable oil
B. Talc
C. Magnesium stearate
D. Boric Acid
149. The main disadvantage of Tragacanth as a binder is that
A. Harden on storage
B. High concentration is required
C. Used in warm condition
D. Incompatible with most of the drugs
150. The decrease in thickness of tablet indicates
A. More hard
B. Less friability
C. Decrease in drug content
D. More disintegration time
151. The thickness of Tablets are measured by
A. Sliding caliper scale
B. Microscopic technique
C. Rotating disc technique
D. Technicon Auto analyser
152. The mesh size of USP disintegrator is
A. 10
B. 5-6
C. 28-32
D. 2.5
153. Enteric coated tablets are initially tested for disintegration is
A. Simulated gastric fluid
B. Simulated intestinal fluid
C. Purified Water
D. Phosphate Buffer (pH-7.4)
154. Cam track are used in tablets for
A. Feeding the granules
B. Fixing the Shape
C. Compressing the granules
D. Building the movement of punches
155. Capping of Tablets can be eliminated by
A. Pre-compression
B. Reducing the final compression rate
C. Using flat punches
D. All of the above
156. Maillard’s reaction is related to
A. Diluent
B. Binder
C. Disintegrants
D. Lubricants
157. Aspartame has the main disadvantage as
A. Carcinogenic
B. Bitter after taste
C. Less sweeter than sucrose
D. Hygroscopic in nature
158. Enteric coating materials are insoluble in gastric media (ph upto 4)being
A. Acid esters
B. Esters
C. Presence of COOH group
D. None of above
159.This tablet is designed to pass unchanged through the stomach to the intestine.
A. Sugar coated tablets
B. Enteric coated tablets
C. Gelatin coated
D. None of above
160. Diclofenac tablet coated with CAP has been administered to a patient, where do you expect the drug to be released?
A. Stomach
B. Oral cavity
C. Small intestine
D. Liver
161. A polymer used to form a hydrophilic matrix of Tablet is………….
A. HPMC
B. CAP
C. EC
D. PE
162. The measurement of cohesive strength of Gelatin molecules that proportional to its molecular weight
of Gelatin is called………….
A. Bloom strength
B. Viscosity
C. Surface Tension
D. Partition co efficient
163. Choose the right sentence.
A. Picking means tablet material adhered to the wall of die cavity.
B. Sticking means tablet material adhered to the wall of die cavity.
C. Sticking means small amount of tablet powder adhered to punch face after compression.
D. Sticking means particles stick to each other and forms a segregated mass.
164. According to USP rotating basket dissolution apparatus is……………..
A. Apparatus I
B. Apparatus II
C. Apparatus III
D. Apparatus IV
165. To avoid pre-systemic metabolism, we should formulate……………
A. Enteric coated tablets
B. Sublingual tablets/ buccal tablets
C. Effervescent Tablets
D. Floating Tablets
166. TiO2 is used as……………
A. Preservative for capsule
B. Plasticizer in capsule
C. Lubricant for tablet
D. Opacifier for Gelatin
167. The ingredients mentioned below are commonly used as the coating agents for film coating except…
A. Cellulose acetate phthalate
B. Carnauba wax
C. Hydroxy ethyl cellulose
D. Sodium carboxy methyl cellulose
168. In a cosmetic preparation an antioxidant used in an aqueous system is……………
A. Sodium formaldehyde sulphoxylate
B. Tocopherol
C. Methyl Paraben
D. Phenol
169. Type A Gelatin is………
A. Acid treated
B. Base treated
C. Salt treated
D. None of above
170. Type B Gelatin is……………
A. Acid treated
B. Base treated
C. Salt treated
D. None of above
171. During Hard Gelatin Capsule manufacturing spinning is carried out for…………..
A. Dry the Gelatin mass
B. Create good cross linked mass
C. Uniformly distribute the Gelatin mass
D. To improve shining
172. It is the example of Anionic detergent of shampoo…………
A. Benzalkonium chloride
B. Cetyl trimethyl ammonium chloride
C. Sodium lauryl sulphate
D. Betains
173. As per USFDA the concentration of Fluoride ions in dentifrices is…………
A. 1 ppm
B. 10 ppm
C. 100 ppm
D. 1000 ppm
174. It is the substance used as film former in Nail lacquers.
A. PEG
B. Nitro cellulose
C. Glycerol
D. HPMC
175. For preparation of Nail lacquer the solvent used should have………….
A. Fastest possible drying rate for rapid effect
B. Controlled drying to prevent skinning and bubbling
C. Slowest possible drying rate
D. Drying of solvent is least important in formulation process
176. Packaging of pharmaceutical product will…….
A. Protect the drug from light and other environmental factors
B. Helps in identifying the drug products
C. Protect from damage occurring during the transportation
D. All of above
177. It is also called as surface treated soda lime glass.
A. USP type I
B. USP type II
C. USP type III
D. USP type IV
178. The following type of Glass is used for packaging of food products
A. USP type I
B. USP type II
C. USP type III
D. USP NP type
179. The following type of Glass is used for packaging of topical products
A. USP type I
B. USP type II
C. USP type III
D. USP NP type
180. If the product containing high amount of alcohol, ethers or organic acids then we should avoid use of………………….. For packaging of these products.
A. Metal
B. Glass
C. Plastic
D. Any of the above can be used
181. The following image is for………….
A. Threaded screw type of closure
B. Lug cap type closure
C. Crown Cap closure
D. Pilfer proof closure
182. The following image is for………….
A. Threaded screw type of closure
B. Lug cap type closure
C. Crown Cap closure
D. Pilfer proof closure
183. The limit of ml of consumption of 0.02 N acids in powder glass test for USP type I glass is…….
A. 1.0 ml
B. 0.7 ml
C. 8.5 ml
D. 15 ml
184. The limit of ml of consumption of 0.02 N acids in powder glass test for USP type III glass is…….
A. 1.0 ml
B. 0.7 ml
C. 8.5 ml
D. 15 ml
185. The limit of ml of consumption of 0.02 N acids in powder glass test for USP type NP glass is…….
A. 1.0 ml
B. 0.7 ml
C. 8.5 ml
D. 15 ml
186. The limit of ml of consumption of 0.02 N acids in water attack test for USP type II (Size <100ml) glass is…….
A. 1.0 ml
B. 0.7 ml
C. 8.5 ml
D. 15 ml
187. According to USP the tablet containing 130 mg average weight passes the weight variation test if, % Difference is……………..
A. 10
B. 7.5
C. 5
D. 3
188. Milling of Drug and excipients mixing if Milled powder Compression to slug screening of Slug Mixing with Lubricants and Disintegrants Compression. These are the steps employed for……..
A. Wet binding
B. Dry binding
C. Direct compression
D. None of above
189. Sodium starch glycolate is not used as a disintegrant if we want to formulate……………
A. Sustain release tablet
B. Immediate release tablet
C. Tablet having rapid onset of action
D. All of above
190. Non uniform distribution of colour on the tablet surface is known as;
A. Mottling
B. Picking
C. Blistering effect
D. Capping
191. Generally the tablets are not accepted, if the friability of that tablets loses their weight;
A. Less than 0.5%
B. Less than 0.75%
C. Less than 1.5%
D. Less than 0.5-1.0%
192. Granule density can be determined by using one of the following.
A. Micrometer
B. Toluene distillation method
C. Pycnometer
D. Coulter-counter method
193. The only artificial sweetener available is;
A. Honey
B. Molasses
C. Saccharin
D. All of above
194. The artificial sweetner is about 500 times sweeter than sucrose and has a bitter after taste is;
A. Mannitol
B. Aspartame
C. Saccharin
D. Sorbitol
195. Fluidized bed dryer is well adopted in the pharmaceutical industry for the drying of;
A. Powder before filling of capsules
B. Granules before compression into tablets
C. Empty capsules before filling
D. Powders before mixing and granulation
196. Which one of the following device is used to increase the efficiency of drug delivery via aerosol?
A. Tube spacers
B. Actuator
C. Metered valve
D. Pressure valve
197. In Aerosol devices, one of the following used to ensure that the aerosol product delivered in the proper and desired form is,
A. Gasket
B. Actuator or button
C. Stem
D. Valve
198. For aerosol dispersion, the surfactant added having the HLB Value;
A. Less than 10
B. More than 10
C. Less than 5
D. More than 20
199. In case of Aerosol formulation, for the filling of aerosol products- the cold filling method required the chilling of all the components, including concentrate and propellant ,to a temperature of;
A. 30 to 40˚F
B. 30 to 40˚C
C. -30 to -40˚F
D. -30 to -40˚C
200. For the filling of aerosol products,-the pressure filling method requires the chilling of all the components, including concentrate and propellant, to a temperature of,
A. Room temperature
B. Refrigerator temp.
C. -30 to -40˚C
D. -30 to -40˚F
201. Hermetically sealed container
A. Protect loss of product during handling
B. Is Impervious to air
C. Is Light resistant
D. Prevent loss of product from effectiveness
202. Hermetic container are used for;
A. Oral solution
B. Powder
C. Injectable
D. None
203. Flaking is a problem associated with container made of:
A. Soda lime glass
B. Borosilicate glass
C. Neutral glass
D. None
204. Soda lime glass not suitable for parenteral solution because.
A. Mechanically weak
B. Release Alkali
C. Losses brilliancy
D. None
205. Which ingredient is added in borosilicate glass to impart chemical stability and heat resistance?
A. Boron
B. Boric oxide
C. Cal-oxide
D. Barium oxide
206. Ampoules is usually made up of;
A. Neutral Glass
B. Borosilicate Glass
C. Soda glass
D. Silicone treated glass
207. Ferrous or manganese oxide is added during the manufacture of glass container to make
A. Alkali resistant
B. Eory mould able
C. Colored glass
D. None
208. Plastic container is not suitable because
A. Permeable to gases
B. Additives leach out from plastic
C. Adsorb ingredient from product
D. All of above
209. Which one is thermosetting plastic?
A. Poly chlorides
B. PVC
C. Phenol formaldehyde
D. Polystyrene
210. Which one of this material is commonly used for closures?
A. Rubber
B. Metal
C. Glass
D. Plastic
211.Which one is used as vulcanizing agent in rubber?
A. Zno
B. S
C. Caco3
D. Znso4
212. Glass container should comply with the
A. Leakage test
B. Hydrolytic resistance
C. Mechanical strength
D. None
213. Hydrolytic resistance test is for
A. Mechanical Strength
B. Liberation Alkali
C. Loss of brilliancy
D. None