Organic Chemistry online test on “Preparation of Amines – 2”.
1. Which of the following reaction does not form amines?
a) RX + NH3 →
b)
c) RCN + H2O (^{underrightarrow{H^+}})
d) RCONH2 + 4H (^{underrightarrow{LiAlH_4}})
Answer: c
Clarification: Nitrile gives carboxylic acid on hydrolysis and amines on reduction.
2. Starting from propanoic acid, the following reactions were carried out, what is the compound Z?
a) CH3−CH2−Br
b) CH3−CH2−NH2
c) CH3-CH2-COBr
d) CH3−CH2−CH2−NH2
Answer: b
Clarification: Starting from propanoic acid, the following reactions were carried out, the compound is ethylamine.
3. In the given equation, what is the final product C?
a) Ammonium acetate
b) Acetamide
c) Amino methane
d) Ethanal
Answer: c
Clarification: Carboxylic acid with PCl5 forms acid chloride and acid chloride reacts with NH3 to give amide which on reduction gives amine.
4. Which of the following reactions will not give primary amine?
a) CH3CONH2 + KOH.Br2
b) CH3CN + LiAlH4
c) CH3NC + LiAlH4
d) CH3CONH2 + LiAlH4
Answer: c
Clarification: Nitrile on reduction gives secondary amine.
5. Gabriel’s phthalimide synthesis is used for the preparation of which amine?
a) Primary aromatic amine
b) Secondary amine
c) Primary aliphatic amine
d) Tertiary amine
Answer: c
Clarification: Gabriel phthalimide synthesis is preferred for synthesising primary amines. Phthalimide is alkylated with alkyl or benzyl halide and then hydrolysed or hydrazinolysis to get pure primary amine.
6. What will be the product of the following reaction?
a) Propanamine
b) N-methylpropaneamine
c) N, N-dimethylpropanemamine
d) Ethyl amine
Answer: a
Clarification: Amides yield primary amines on reduction by lithium aluminium hydride.
