Pharmacy MCQs and Answers
1. Total number of Axial bone in adult human body
A. 126
B. 80
C. 206
D. 202
Answer: B
2. Indian senna obtained from the plant
A. Cassia angustifolia
B. Cassia acutifolia
C. Cassia obovata
D. Cassia auriculata
Answer: A
3. What is the descriptive name of clotting factor X
A. Fibrinogen
B. Labile factor
C. Prothrombin
D. Stuart-Prower factor
Answer: D
4. Which among the following is a sterile preparation
A. Nasal drops
B. Effervescent granules
C. Ophthalmic Preparations
D. Otic Preparations
Answer: C
5. Which among the following drug formulation is required to be stored in refrigerator
A. Emulsions
B. Suspensions
C. Vaccines
D. Non of the above
Answer: C
6. Which among the following is a liquid alkaloid
A. Nicotine
B. Strychnine
C. Quinine
D. Colchicine
Answer: A
7. Schedule R of Drugs and Cosmetic Act deals with
A. Disinfectants
B. Antiseptics
C. Mechanical Contraceptives
D. Dyes,Colours & Pigments
Answer: C
8. Sterilization condition by Steam Sterilization of Injection as per IP
A. 121°C at 15psig for 30 minutes
B. 171°C at 15psig for 1 hour
C. 135°C at 15psig for 15 minutes
D. 134°C at 15psig for 15 minutes
Answer: A
9. One table spoon is equivalent to
A. 10ml
B. 15 ml
C. 20 ml
D. 5 ml
Answer: B
10. Iatrogenic disease means
A. Drug induced disease
B. Systemic infections
C. Physician induced desease
D. Contagious disease
Answer: C
11. Major chemical constituent present in the clove oil
A. Fenchone
B. Citral
C. AnetholC
D. Eugenol
Answer: D
12. Vitali-Morin test is used to identify
A. Indole alkaloids
B. Isoquinoline alkaloids
C. Tropane alkaloids
D. Purine Alkaloids
Answer: C
13. Synonym of Chlorinated lime
A. Sodium hypochlorite
B. Calcium chloride
C. Chlorhexinol
D. Bleaching powder
Answer: D
14. Agar is obtained from the
A. Green algae
B. Blue algae
C. Red algae
D. Blue green algae
Answer: C
15. Locally applied protein precipitants are called
A. Astringents
B. Antiseptics
C. Disinfectants
D. Protectives
Answer: A
16. Chemically Paraldehyde is
A. Sodium-2,2,2-trichloroethyl hydrogen orthophosphate
B. 2,4,6 Trimethyl-1,3,5 trioxane
C. 3,3-Diethyl-5-methyl pipridine-2,4-dione
D. 3-Ethyl-3-phenyl piperidine-2,6 dione
Answer: B
17. Clofibrate is used as a
A. Lipid lowering agent
B. Antiarrhythmic drug
C. Antiinflammtory drug
D. Antianginal drug
Answer: A
18. Biotin acts as a coenzyme in which type of reactions
A. Carboxylation
B. Acetylation
C. Dehydrogenation
D. Transamination
Answer: A
19. Diphenhydramine is a derivative of
A. Ethylene diamine
B. Phenothiazines
C. Aminoalkyl ethers
D. Alkyl amines
Answer: C
20. Heterocyclic ring present in Indomethacin
A. Imidazole
B. Indole
C. Indoline
D. Quinoline
Answer: B
21. SSRI useful in the treatment of premature ejaculation
A. Dapoxetine
B. Duloxetine
C. Venlafaxine
D. Sertraline
Answer: A
22. In a clinical trial, comparison of efficacy of a new drug with an existing drug is done in
A. Phase I
B. Phase II
C. Phase III
D. Phase IV
Answer: C
23. All of the following are short acting insulin analogs except
A. Insulin lispro
B. Insulin aspart
C. Insulin glargine
D. Insulin glulisine
Answer: C
24. Etravirine is
A. Nucleoside reverse transcriptase inhibitor
B. Non nucleoside reverse transcriptase inhibitor
C. Integrase inhibitor
D. Entry inhibitor
Answer: B
25. Physiological salt solution used for mammalian smooth muscle experiments
A. Tyrode solution
B. Frog ringer solution
C. De Jalon solution
D. Mc even solution
Answer: A
26. Drug most likely to cause malignant hyperthermia is
A. Propofol
B. Ketamine
C. Halothane
D. Thiopentone sodium
Answer: C
27. Squalene epoxidase inhibitor is
A. Terbinafine
B. Griseofulvin
C. Miconazole
D. Tolnaftate
Answer: A
28. Penicillin G is the drug of choice in
A. Rickettsial infection
B. Leptospirosis
C. Typhoid
D. Bacterial dysentery
Answer: B
29. CAMP is the second messenger for the following receptors except
A. Histamine `”H_2″`
B. Adrenergic `beta`
C. Serotonin `5HT_2`
D. Dopamin `D_1`
Answer: C
30. Glucocorticoid with the least mineralocorticoid activity is
A. Deflazacort
B. Prednisolone
C. Methylprednisolone
D. Hydrocortisone
Answer: A
31. Ocular anti inflammatory agent among the following
A. Flurbiprofen
B. Indomethacin p-0
C. Mefenamic acid
D. Piroxicam
Answer: A
32. NMDA receptor antagonist useful in Alzheimer’s disease
A. Galantamine
B. Memantine
C. Donepezil
D. Co Dergocrine
Answer: B
33. Uses of ACE inhibitors are all except
A. Hypertension
B. Congestive cardiac failure
C. Myocardial infarction
D. Variant angina
Answer: D
34. Teriparatide can be used for the treatment of
A. Osteoporosis
B. Polycystic ovarian disease
C. Hyperparathyroidism
D. Hypocalcemia
Answer: A
35. Drug of choice in trigeminal neuralgia
A. Carbamazepine
B. Phenytoin
C. Lamotrigine
D. Sodium valproate
Answer: A
36. Conversion of T4 to T3 is inhibited by all EXCEPT
A. Propranolol
B. Propylthiouracil
C. Carbimazole
D. Amiodarone
Answer: C
37. Diuretic with anti remodelling action
A. Furosemide
B. Hydrochlorothiazide
C. Amiloride
D. Spironolactone
Answer: D
38. Mu receptor is responsible for all the following effects EXCEPT
A. Miosis
B. Bronchodilation
C. Euphoria
D. Hypothermia
Answer: B
39. Most cardiotoxic local anaesthetic is
A. Procaine
B. Prilocaine
C. Bupivacaine
D. Tetracaine
Answer: C
40. A normal distribution curve depends on
A. Mean and sample size
B. Mean and median
C. Range and sample size
D. Mean and standard deviation
Answer: D
41. Non sugar parts of the glycosides are called
A. Aglycon
B. Glycon
C. Glycogen
D. Glycol
Answer: A
42. All are Heterocyclic alkaloids except
A. Nicotine
B. Strychnine
C. Ergotamine
D. Ephedrine
Answer: D
43. Vitamin present in Coenzyme A
A. Riboflavin
B. Pyridoxine
C. Biotin
D. Pantothenic acid
Answer: D
44. Which among the following is a Non Reducing sugar
A. Sucrose
B. Glucose
C. Maltose
D. Lactose
Answer: A
45. Latest edition of Indian Pharmacopoeia was published in the year
A. 1996
B. 2014
C. 2010
D. 2007
Answer: B
46. Use of Potassium Iodide in Iodune solution
A. Increase the solubility of Iodine
B. Decrease the solubility of Iodine
C. Reduce the toxicity of Iodine
D. Improve the apearance of Iodine solution
Answer: A
47. How much of 7 Percentage solution will be required to prepare 250 ml of 1 in 100 Solution
A. 0.026 ml
B. 2.8 ml
C. 7 ml
D. 35.71 ml
Answer: D
48. Term used to describe Partial OR Complete separation of Top or Bottom of the tablet
A. Lamination
B. Capping
C. Picking
D. Chipping
Answer: B
49. Drug of choice for filariasis
A. Carbamazepine
B. Diethyl succimide
C. Diethyl Carbamazine
D. Carbimazole
Answer: C
50. Antibiotic which causes Gray Baby Syndrome
A. Gentamicin
B. Doxorubicin
C. Chloramphenicol
D. Amikacin
Answer: C
51. An example for an anthracene glycoside
A. Purpurea glycoside
B. Diosgenin
C. Cantharidin
D. Sennoside
Answer: D
52. Hydrogen Peroxide IP used as antiseptic contains
A. 100% w/v of Hydrogen peroxide
B. 25% w/v of Hydrogen Peroxide
C. 6% w/v of Hydrogen Peroxide
D. 27% w/v of Hydrogen Peroxide
Answer: C
53. The agent used as a radio-opaque contrast medium:
A. Radioactive Sodium Iodide
B. Colloidal Gold Injection
C. Barium Sulphate
D. Sodium Iodo hippurate
Answer: C
54. When an hypotonic solution is injected into blood stream, causes
A. Haemolysis
B. Shrinkage of blood cells
C. Sclerosis of veins
D. No characteristic change
Answer: A
55. Sodium lauryl Sulphate is
A. Cationic surface active agents
B. Ampholytic surface active agents
C. Nonionic surface active agents
D. Anionic surface active agents
Answer: D
56. A toxoid vaccine is:
A. Killed bacterial suspension
B. Live bacterial suspension
C. Live viral Vaccine
D. Toxins that have been incubated with for malin
Answer: D
57. 0.1gms contains:
A. 1000 mg
B. 100 mg
C. 10 mg
D. 1 mg
Answer: B
58. Volume of 95% alcohol required to prepare 500 ml of 20% alcohol is:
A. 80 ml
B. 50 ml
C. 105 ml
D. 150 ml
Answer: C
59. Which among the following is a blood coagulation factor:
A. Sodium
B. Calcium
C. Potassium
D. Manganese
Answer: B
60. An example for a drug that undergoes extensive first pass metabolism:
A. Testosterone
B. Phenobarbitone
C. Tolbutamide
D. Theophylline
Answer: A
61. Which among the following is NOT a first line drug for the treatment of Tuberculosis
A. Rifampicin
B. Ethionamide
C. Isoniazide
D. Ethambutol
Answer: B
62. Which among the following is a first generation Cephalosporin
A. Cefepime
B. Cefuroxime
C. Cefixime
D. Cephalexin
Answer: D
63. Which of the following is NOT the use of Propranolol
A. Glaucoma
B. Cataract
C. Migraine
D. Hypertension
Answer: B
64. Vitamin present in the shark liver oil
A. Vitamin A
B. Vitamin D
C. Vitamin K
D. Vitamin E
Answer: A
65. Who is the Secretary of Pharmacy and Therapeutic Committee
A. Administrator
B. Pharmacist
C. Medical Director
D. Chief Physician
Answer: B
66. Which among the following drug induce hepatic microsomal enzymes
A. Isoniazid
B. Phenylbutazone
C. Cimetidine
D. Phenytoin
Answer: D
67. Which among the following preparation is applied to body cavity
A. Collodion
B. Liniments
C. Douches
D. Paints
Answer: C
68. 1mg is equivalent to
A. 1000μg
B. 100μg
C. 10μg
D. 50μg
Answer: A
69. example for preservative added in whole human blood
A. Phenyl mercuric acetate
B. Phenyl mercuric nitrate
C. Phenol
D. No preservative
Answer: D
70. Meaning of latin term “primo mane”
A. As directed
B. Breakfast
C. During night
D. Early in the morning
Answer: D
71. An inherited metabolic disorder Alkaptonuria is due to the lack of enzyme
A. Phenylalanine hydroxylase
B. Tyrosine hydroxylase
C. Homogentisate oxidase
D. Hydroxy phenylpyruvate hydroxylase
Answer: C
72. Synthetic analogue of Vitamin K
A. Menadione
B. Coumarins
C. Warfarin sodium
D. Heparin
Answer: A
73. “Caution it is dangerous to take this preparation except under medical supervision” should be included in the label of
A. Schedule G drugs
B. Schedule H drugs
C. Schedule X drugs
D. Schedule C drugs
Answer: A
74. Plant steroid used as a precursor for the synthesis of cortico steroid
A. Solanine
B. Diosgenin
C. Solanidine
D. Veratridine
Answer: B
75. The drug which cause Oto toxicity
A. Azithromycin
B. Doxycycline
C. Neomycin
D. Erythromycin
Answer: C
76. Which among the following Vitamin have a Naphthaquinone ring
A. Vitamin E
B. Vitamin K
C. Vitamin D
D. Vitamin B12
Answer: B
77. Alcohol present in the Spingolipid
A. Sphingosine
B. Sphinganine
C. Sphingomyleine
D. Ceramide
Answer: A
78. Which agency advices government and DTAB on issues related to uniform operation of D&C Act throughout the Country
A. Drug Consultative Committe
B. Central Drugs Laboratory
C. Drugs Control Department
D. Central Drugs Research Institute
Answer: A
79. Devil’s dung is the synonym of
A. Myrrh
B. Asafoeitida
C. Digitalis
D. Ginseng
Answer: B
80. Disease characterized by increase in the number of platelets in blood
A. Lymphocytic leukemia
B. Megaloblastic anemia
C. Thrombocytopenia
D. Thrombocythemia
Answer: D
81. Which of the following general anaesthetic has poor muscle relaxant action?
A. Ether
B. Nitrous oxide
C. Halothane
D. Ketamine
Answer: B
82. The dose limiting toxicity of doxorubicin is
A. Hepatic centrilobular necrosis
B. Congestive cardiac failure
C. Proximal tubular necrosis
D. Peripheral neuropathy
Answer: B
83. Characteristic feature of piperacillin is
A. Acid labile and penicillinase resistant
B. Acid resistant and penicillinase labile
C. Acid labile and penicillinase labile
D. Acid resistant and penicillinase resistant
Answer: C
84. Cytochrome P450 isoenzyme involved in the metabolism of most of the drugs is
A. CYP2E1
B. CYP2D6
C. CYP3A4
D. CYP2C19
Answer: C
85. Antipsychotic with prokinetic action
A. Levosulpiride
B. Amisulpride
C. Loxapine
D. Pimozide
Answer: A
86. Centrally acting skeletal muscle relaxant that acts via `alpha2` adrenergic agonism
A. Tizanidine
B. Brimonidine
C. Baclofen
D. Chlormezanone
Answer: A
87. Which of the following is a phase 2 reaction?
A. Oxidation
B. Acetylation
C. Hydrolysis
D. Reduction
Answer: B
88. All of the following are anti seizure drugs useful for migraine prophylaxis except
A. Gabapentin
B. Topiramate
C. Vigabatrin
D. Sodium valproate
Answer: C
89. The following are mixed agonist antagonist except
A. Pentazocine
B. Nalbuphine
C. Fentanyl
D. Nalorphine
Answer: C
90. Chlorpromazine has all the following actions in addition to its anti dopaminergic effect except
A. Anticholinergic action
B. Antihistaminic action
C. Alpha adrenergic blocking action
D. Beta adrenergic blocking action
Answer: D
91. Bacillus Calmette Guerin Vaccine is
A. Suspension of living cells of a strain of Mycobacterium tuberculosis
B. Suspension of living cells of a strain o
f Bordetella pertusis
C. Suspension of living cells of a strain of Salmonella typhi
D. Suspension of living cells of a strain of Vibrio cholerae
Answer: A
92. The toxic protein present in castor oil is
A. Ricinoleic acid
B. Ricin
C. Isoricinoleic acid
D. Linoleic acid
Answer: B
93. Calamine IP is
A. Aluminium silicate with ferric oxide
B. Magnesium silicate with ferric oxide
C. Calcium oxide with ferric oxide
D. Zinc oxde with ferric oxide
Answer: D
94. Which among the following statement is false with respect to NaCl Injection I P
A. Contains 0.9% w/v sterile solution of Sodium Chloride
B. pH of the solution is between 4.5 & 7.0
C. Contains added antimicrobial agents or preservatives
D. Contains approximately 150 mmol of Sodium ions
Answer: C
95. Which one of the following is used as an antimicrobial preservative:
A. Propylene glycol
B. Procaine hydrochloride
C. Propyl hydroxy benzoate
D. Sodium hydrogen carbonate
Answer: C
96. Cotrimoxazole tablet contains:
A. 5 parts of Cortisone acetate and 1 parts of trimethoprim
B. 5 parts of Sulphamethoxaole and 1 parts of trimethoprim
C. 5 parts of Sulphasalazine and 1 parts of trimethoprim
D. 5 parts of Cloxacillin and 1 parts of trimethoprim
Answer: B
97. Which among the following is used as a diuretic:
A. Tribulus terrestris
B. Claviceps purpurea
C. Cyamopsis tetragonolobus
D. Commiphora molmol
Answer: A
98. Potassium permanganate is an example for:
A. acidifying agent
B. alkalising agent
C. reducing agent
D. oxidising agent
Answer: D
99. Lugols Solution is:
A. 2.5%w/v of Iodine and 2.5% w/v of potassium iodide in water
B. 10.0%w/v of Iodine and 6.0% w/v pf potassium iodide in water
C. 5.0%w/v of Iodine and 10.0% w/v of potassium iodide in water
D. 2.0% w/v of Iodine and 2.4 % w/v of Sodium iodide in water
Answer: C
100. Ammonium Chloride is used as:
A. Alkalising agent
B. Astringent
C. Expectorant
D. All the above
Answer: C
101. Pyridoxine is
A. Vitamin B 1
B. Vitamin B 2
C. Vitamin B 6
D. Folic acid
Answer: C
102. The latin term “Oris” denotes
A. to mouth
B. Ever hour
C. when necessary
D. at bed time
Answer: A
103. Carbonic anhydrase inhibitor
A. Ethacrynic acid
B. Chlorothiazide
C. Acetazolamide
D. Chlorothiazide
Answer: C
104. Which one among the following has a phenanthrene nucleus:
A. Pentazocine
B. Trifluperazine
C. Promethazine
D. Morphine
Answer: D
105. 2 Acetoxy benzoic acid is:
A. Paraben
B. Aspirin
C. PABA
D. Benzocaine
Answer: B
106. An agent used to delay the renal excretion of penicillins
A. Protamine sulphate
B. Procaine
C. Propylene glycol
D. Probenecid
Answer: D
107. An antidote for warfarin toxicity/overdose
A. Protamine
B. Dimercaprol
C. Penicillamine
D. Vitamin K
Answer: D
108. An ingredient of anticoagulant solution used for storage of whole blood
A. Anhydrous citric acid
B. Anhydrous benzoic acid
C. Anhydrous Tartaric acid
D. Ascorbic acid
Answer: A
109. Valproic acid is used as an
A. Analgesic
B. Antiepileptic
C. Anti-inflammatory
D. Diuretic
Answer: B
110. All the following General anaesthetics are administered intravenously except:
A. Ketamine
B. Propofol
C. Halothane
D. Thiopentone Sodium
Answer: C
111. In tablet manufacturing, TALC is used as
A. Diluent
B. Granulating agent
C. Glidant
D. Disintegrating agent
Answer: C
112. SCHICK TEST is done to
A. Detect the degree of immunity against Diphtheria.
B. Detect the degree of immunity against Tuberculosis
C. Detect the degree of immunity against Typhoid
D. identify the presence of Ketone bodies in urine
Answer: A
113. Glycerin or Sorbitol is added to gelatin in the preparation of soft gelatin capsules as
A. Preservatives
B. Plasticizer
C. Polishing agent
D. Sweetening agent
Answer: B
114. Principle of Size Reduction in Ball Mill is
A. Compression
B. Impact
C. Attrition
D. Combination of Impact and Attrition
Answer: D
115. Eugenia caryophyllus is the botanical name of
A. Clove
B. Eucalyptus
C. Coriander
D. Cardamom
Answer: A
116. Who among the following is not an Ex-officio member of central council of Pharmacy Council of India
A. Director General, Health Services
B. Drugs Controller of India
C. Director, Central Drugs Laboratory
D. Health Secretary, Govt. of India
Answer: D
117. The limit test of Iron depends upon the interaction of iron with
A. Barium Sulphate reagent
B. Diphenyl thiocarbazone
C. Thioglycollic acid
D. Mercuric Chloride
Answer: C
118. In relation to emulsion, formation of a layer of relatively concentrated emulsion above or below the surface is known as
A. Cracking
B. Creaming
C. Mottling
D. Phase inversion
Answer: B
1119. Drugs Inspector is appointed as per the provisions of
A. Pharmacy Act 1948
B. Drugs and Cosmetics Act 1945
C. Drugs Inspector Act 1940
D. Narcotic and Psychotropic Substances Act 1985
Answer: B
120. Presence of lignified trichomes is the characteristic microscopic feature of
A. Nux-vomica
B. Digitalis
C. Datura
D. Cinchona
Answer: A
121. Valbenazine is
A. VMAT2 inhibitor
B. MAO-B inhibitor
C. COMT inhibitor
D. MAO-A inhibitor
Answer: A
122. Concerning streptogramin, which of the following statement is false?
A. Active against MRSA
B. Induce cytochrome P450 enzyme
C. Useful against vancomycin resistant enterococci
D. Excreted mainly through feces
Answer: B
123. The minimal alveolar concentration of an inhalational anaesthetic is a measure of its
A. Potency
B. Therapeutic index
C. Diffusibility
D. Efficacy
Answer: A
124. First line ACT under NVBDCP for chloroquine resistant falciparum malaria
A. Artesunate + sulfadoxine + pyrimethamine
B. Artemether + lumefantrine
C. Artesunate + mefloquine
D. Arterolane + piperaquine
Answer: A
125. About first order kinetics, true statement is
A. Fixed amount of the drug is eliminated
B. Clearance remains constant
C. Half-life increases with dose
D. Decreased clearance with increase in dose
Answer: B
126. Antagonism between adrenaline and histamine is
A. Physical antagonism
B. Physiological antagonism
C. Competitive equilibrium antagonism
D. Competitive non equilibrium antagonism
Answer: B
127. Which of the following is not associated with hydrochlorothiazide treatment
A. Hyponatremia
B. Hypokalemia
C. Hypocalcemia
D. Hyperuricemia
Answer: C
128. Aminoglycosides are not useful in the treatment of infections with
A. Pseudomonas
B. E Coli
C. Klebsiella
D. Clostridium difficile
Answer: D
129. Drug preferred in the treatment of swine flu
A. Abacavir
B. Oseltamivir
C. Acyclovir
D. Tenofovir
Answer: B
130. The name of ahlquist is associated with
A. Classification of cholinergic receptors
B. Classification of adrenergic receptors
C. Classification of histamine receptors
D. Classification of serotonin receptors
Answer: B
131. Organophosphorous poisoning is treated with
A. Acetylcholine
B. Atropine
C. Pentazocine
D. Methacholine
Answer: B
132. Benzodiazepine receptor antagonist:
A. Flumazenil
B. Atropine
C. Pentazocine
D. Phentolamine
Answer: A
133. Diabetes insipidus is due to deficiency of :
A. Oxytocin
B. Insulin
C. Vasopressin
D. Aldosterone
Answer: C
134. Epsom Salt is
A. Copper Sulphate
B. Magnesium Sulphate
C. Ferrous Sulphate
D. Calcium Sulphate
Answer: B
135. In combination antacids, Magnesium salts are added:
A. for immediate onset of action
B. to decrease the production of acid in GIT
C. to enhance taste and appearance
D. for laxative action
Answer: D
136. Directly observed treatment, Short course (DOTS) refers to:
A. AIDS control strategy of Govt of India
B. Strategic action plan for Malarial control in India
C. Tuberculosis control strategy, recommended by WHO
D. part of National Filaria control program
Answer: C
137. An Adverse effect of Clozapine
A. Agranulocytosis
B. Nephrotoxicity
C. Hepatotoxicity
D. Respiratory depression
Answer: A
138. Antixerophthalmic vitamin is
A. Vitamin E
B. Vitamin D
C. Vitamin B
D. Vitamin A
Answer: D
139. Lanolin is
A. Beeswax
B. Woolfat
C. Paraffin wax
D. Borax
Answer: B
140. Ratio of oil:water:gum for preparing an emulsion using volatile oil:
A. 2:2:1
B. 4:2:1
C. 3:2:1
D. 1:1:2
Answer: A
141. All of the following are disease modifying anti-rheumatoid drugs except
A. Etanercept
B. Anakinra
C. Infliximab
D. Cetuximab
Answer: D
142. Glycoprotein IIb/IIIa receptor antagonist is
A. Prasugrel
B. Ticlopidine
C. Tirofiban
D. Cangrelor
Answer: C
143. Preferred drug in the treatment of drug induced parkinsonism
A. Levodopa
B. Selegiline
C. Trihexyphenidyl
D. Tolcapone
Answer: C
144. Stimulation of which receptor will release renin?
A. Alpha 1
B. Alpha 2
C. Beta 1
D. Beta 2
Answer: C
145. Evolocumab is used in
A. Hyperlipidemia
B. Bronchial asthma
C. Migraine
D. Breast cancer
Answer: A
146. 5-HT1A partial agonist among the following
A. Ketanserin
B. Hydroxyzine
C. Cyproheptadine
D. Buspirone
Answer: D
147. All of the following can be used as local anaesthetics except
A. Dexmedetomidine
B. Centbucridine
C. Diphenhydramine
D. Benzyl alcohol
Answer: A
148. All of the following drugs are included under RNTCP for the treatment of XDR-TB except
A. Capreomycin
B. Levofloxacin
C. Clofazimine
D. Linezolid
Answer: B
149. Denosumab is used for the treatment of
A. Rheumatoid arthritis
B. Osteoarthritis
C. Osteoporosis
D. Systematic lupus erythematosus
Answer: C
150. Anthelmintic agent with immunomodulatory action
A. Albendazole
B. Pyrantel pamoate
C. Piperazine
D. Levamisole
Answer: D
151. An antidote which can be used in cyanide poisoning:
A. Sodium bicarbonate
B. Sodium nitrite
C. Dimercaprol
D. Sodium bi sulphite
Answer: B
152. Colloidal dispersion of liquids or solids in gases are:
A. Aerosols
B. Emulsion
C. Creams
D. Suspensions
Answer: A
153. An example for a drug with anti-hypertensive action
A. Rhubarb
B. Vasaka
C. Liquorice
D. Rauwolfia
Answer: D
154. Restricted licences in Forms 20-A and 21-A are issued for:
A. Narcotic and Psychotropic substances
B. Pethidine and related drugs
C. wholesale dealing of drugs which does not require the supervision of a registered pharmacist
D. drugs specified in Schedule X
Answer: C
155. The Schedule in Drugs and Cosmetics Actwhich specifies that drugs shall not be sold by retail except on and in accordance with the prescription of a Registered Medical Practitioner:
A. Schedule K
B. Schedule G
C. Schedule J
D. Schedule H
Answer: D
156. As per Drugs and Cosmetics Act 1945, the term “Drugstore” refers to
A. Licenses where the service of registered
B. Licenses who employ the service of regispharmacist is employed but donot maintain a pharmacytered pharmacist and maintain a pharmacy for compounding against prescription
C. Licenses where drugs are temporarily stored
D. Licenses where service of a qualified person is not required
Answer: D
157. Which among the following is a prodrug:
A. Levodopa
B. Indomethacin
C. Paracetamol
D. Diphenhydramine
Answer: A
158. Leucovorin rescue is given to reduce the toxic effects of
A. Methotrexate
B. Cyclophosphamide
C. Melphalan
D. Chlorambucil
Answer: A
159. The antibiotic that acts by inhibiting bacterial protein synthesis by binding to the 30s ribosomal subunits:
A. Chloramphenicol
B. Doxycyclin
C. Azithromycin
D. Vancomycin
Answer: B
160. Diethyl carbamazine is the drug of choice in the treatment of:
A. Epilepsy
B. Filarial infection
C. Hookworm infestation
D. Malaria
Answer: B
161. Inhgverse agonist of benzodiazepine receptor is
A. Flumazenil
B. Gabapentin
C. Beta carboline
D. Zopiclone
Answer: C
162. All are properties of digoxin except
A. Low steady margin
B. High volume of distribution
C. inhibits Na+K+ATPase
D. Metabolized in liver
Answer: D
163. Febuxostate is
A. Non purine inhibitor of xanthine oxidase
B. Used in acute gout
C. Uricosuric drug
D. Given intravenously
Answer: A
164. The drug with the least oral bioavailability among the following
A. Ampicillin
B. Gentamicin
C. Doxycycline
D. Ciprofloxacin
Answer: B
165. Prostaglandin analog used in the treatment of constipation predominant IBS
A. Lubiprostone
B. Alosetron
C. Prucalopride
D. Cisapride
Answer: A
166. A metal chelator which can be used in the treatment of a collagen vascular disease but may precipitate yet another collagen vascular disease
A. Penicillamine
B. Desferrioxamine
C. Dimercaprol
D. Calcium disodium edetate
Answer: A
167. Neurokinin receptor antagonist used in the treatment of chemotherapy induced vomitting
A. Dronabinol
B. Ondansetron
C. Aprepitant
D. Rimonabant
Answer: C
168. All are pharmacogenetically mediated reactions except
A. Adenosine deaminase deficiency
B. Succinylcholine apnoea
C. Coumarin insensitivity
D. G6PD deficiency
Answer: A
169. Which one of the following antimicrobial agent has got a ketolide structure
A. Linezolid
B. Streptogramins
C. Aztreonam
D. Telithromycin
Answer: D
170. Preferred drug for the treatment of pneumocystis Jiroveci Pneumonia
A. Erythromycin
B. Co-trimoxazole
C. Doxycycline
D. Clindamycin
Answer: B
171. Acetazolamide inhibits the enzyme
A. Alcohol dehydrogenase
B. Aldehyde dehydrogenase
C. Carbonic anhydrase
D. pyruvate dehydrogenase
Answer: C
172. Viscosity of Agar solution is due to the presence of
A. Agarose
B. Cellulose
C. Agaropectin
D. cellobiose
Answer: C
173. Which among the following is not an anti thyroid drug
A. Carbimazol
B. Levothyroxine sodium
C. Propylthiouracil
D. Iodine
Answer: B
174. Anti estrogen used for the treatment of infertility
A. Tamoxifen
B. Ibuprofen
C. Naproxen
D. Clomifene
Answer: D
175. Drugs which contain Catechol nucleus
A. Nor adrenalin
B. Ephedrine
C. Phenylephrine
D. Pseudo ephedrin
Answer: A
176. Hydrous wool fat is known as
A. Lanolin
B. Macrogoal
C. Cholestrol
D. Lecithin
Answer: A
177. Repacking license are granted in drugs specified in following schedules except
A. Schedule X
B. Schedule C & C1
C. Schedule H
D. Schedule O
Answer: B
178. Antidot used for the treatment of organo phosphorous poisoning
A. Physostigmine
B. Pyridostigmine
C. Pralidoxime
D. Pilocarpine
Answer: C
179. Toxic principle present in the castor seed
A. resino tannic acid
B. Recinoleic acid
C. Isorecinoleic acid
D. Ricin
Answer: D
180. Schedule M1 of Drugs and Cosmetics Act 1940 & Rules 1945 deals with
A. Allopathic medicines
B. Homeopathic medicines
C. Medical devices
D. Cosmetics
Answer: B
181. Clavulanic acid is given along with amoxycillin to
A. decrease excretion
B. avoid first pass metabolism
C. prevent drug resistance
D. enhance oral absorption
Answer: C
182. Carbidopa is used for the treatment of parkinsonism because it
A. crosses blood brain barrier
B. decrease monoamine oxidase
C. inhibits L aminoacid decarboxylase
D. a COMT inhibitor
Answer: C
183. Aldosterone antagonist
A. Spironolactone
B. Amiloride
C. Mannitol
D. Acetazolamide
Answer: A
184. Antimalarial drug used in Rheumatoid arrthritis
A. Mepacrine
B. Chloroquine
C. Artemisine
D. Pamaquine
Answer: B
185. Selenium Sulfide is used as
A. Antimalarial
B. Antileprotic
C. Antifungal
D. Antidandruff
Answer: D
186. The process of loosing water of crystallisation from a substance is
A. Exudation
B. Efflorescence
C. Delequescence
D. Diaphoretic
Answer: B
187. Plantago ovata is used as
A. Expectorant
B. Sweetening agent
C. Analgesic
D. Laxative
Answer: D
188. Sucrose is a
A. Hexose
B. Monosaccharides
C. Disaccharides
D. Polysaccharides
Answer: C
189. An antidiabetic plant drug:
A. Withania somnifera
B. Saraca indica
C. Urginea maritima
D. Gymnema sylvestre
Answer: D
190. A tropane alkaloid:
A. Atropine
B. Reserpine
C. Ergometrine
D. Diosgenin
Answer: A
191. Domperidone is
A. `”5HT_3″` antagonist
B. `”5HT_4″` agonist
C. D2 antagonist
D. D2 agonist
Answer: C
192. Drug of choice in neurocysticercosis
A. Praziquantel
B. Albendazole
C. Ivermectin
D. Pyrantal pamoate
Answer: B
193. Stiripentol is an
A. Antipsychotic
B. Antiepileptic
C. Antiparkinsonian
D. Antidepressant
Answer: B
194. All are catecholamines except
A. Epinephrine
B. Norepinephrine
C. Dopamine
D. Phenylephrine
Answer: D
195. Fastest acting antimalarial drug
A. Chloroquine
B. Quinine
C. Mefloquine
D. Artesunate
Answer: D
196. The mechanism of action of sofosbuvir is
A. NS5B polymerase inhibitor
B. NS5A inhibitor
C. NS3 Protease inhibitor
D. Neuraminidase inhibitor
Answer: A
197. Drug which is not of microbial origin
A. Lovastatin
B. Ivermectin
C. Paclitaxel
D. Sirolimus
Answer: C
198. Essential drugs are
A. Life saving drugs
B. Drugs meeting the health needs of majority of population
C. Drugs that must be available in emergency departments
D. Drugs that are listed in pharmacopoeia of a nation
Answer: B
199. Loading dose of a drug primarily depends on
A. Volume of distribution
B. Clearance
C. Rate of administration
D. Plasma half-life
Answer: A
200. Selective estrogen receptor down regulator is
A. Clomiphene citrate
B. Toremifene
C. Letrozole
D. Fulvestrant
Answer: D
201. Which one of the following is referred to as Good Cholesterol:
A. Triglycerides
B. High density Lipoproteins
C. Low density Lipoproteins
D. Chylomicrons
Answer: B
202. Which part of the plant “Opium poppy” is used for obtaining the active principles:
A. dried latex from stem
B. dried latex from capsules
C. dried latex from root
D. dried latex from shoots
Answer: B
203. Proton pump inhibitor used in the treatment of peptic ulcer
A. Rabeprazole
B. Ranitidine
C. Misoprostol
D. Sucralfate
Answer: A
204. An example for a drug that induces cytochrome P450:
A. Phenytoin
B. Omeprazole
C. Allopurinol
D. Chloramphenicol
Answer: A
205. Physostigmine is an example for
A. Adrenergic durg
B. Anticholinergic drug
C. Adrenergic blocking drug
D. Anticholinesterase
Answer: D
206. A Non Steroidal Anti Inflammatory Drug derived from anthranilic acid:
A. Mephenemic acid
B. Ibuprofen
C. Indomethacin
D. Diclofenac Sodium
Answer: A
207. A hormone secreted by the anterior lobe of pituitary gland:
A. Mineralocorticoids
B. Gonadotropin releasing hormone
C. Growth hormone
D. Thyrotropin releasing hormone
Answer: C
208. An drug which inhibits spermatogenesis, used as male contraceptive
A. Tamoxifen
B. Norethindrone
C. Levonorgestrel
D. Gossypol
Answer: D
209. An Angiotensin antagonist:
A. Captopril
B. Losartan
C. Verapamil
D. Nicorandil
Answer: B
210. Lovastatin is
A. Antifibrinolytic agent
B. H2 receptor antagonist
C. HMG Co-A reductase inhibitor
D. Lipoprotein lipase activator
Answer: C
211. Which of the following is not an instability problem of emulsion
A. Creaming
B. Phase inversion
C. Cracking
D. Flashing
Answer: D
212. Which among the following is used as a systemic acidifier
A. Potassium iodide
B. Potassium citrate
C. Ammonium Chloride
D. Sodium acetate
Answer: C
213. Radioisotope P-32 used for the treatment of
A. Hyperthyroidism
B. Carcinoma of bone
C. Thyroid cancer
D. Polycythemia vera
Answer: D
214. Which among the following is used as a filtering aid
A. Calcium carbonate
B. Hydroxy methyl cellulose
C. Methyl cellulose
D. Kaolin
Answer: D
215. Radiopaque contrast media used for the X-ray examination of Gastro intestinal tract
A. Barium chloride
B. Barium sulphite
C. Barium sulphide
D. Barium Sulphate
Answer: D
216. Which among the following is used to prepare Anti-Rust tablet
A. Sodium chloride
B. Sodium sulphate
C. Sodium nitrite
D. Sodium metabisulphate
Answer: C
217. Method for mixing potent drug powder with large volume of diluent is
A. Tumbling
B. Geometric dilution
C. Swifting
D. Levigation
Answer: B
218. Modified Brontagers test are used to identify which type of Anthraquinone glycosides
A. O-glycosides
B. N-glycosides
C. C-glycosides
D. S-glycosides
Answer: C
219. Cinnamon is marketed in the form of
A. Compound quills
B. Double quills
C. Simple quills
D. Channelled
Answer: A
220. Heavy and light Magnesium oxides differ in their
A. Water of hydration
B. Solubility
C. Molecular weight
D. Bulk density
Answer: D
221. A state of decreased responsiveness to the pharmacologic effect of a drug resulting from prior exposure to that drug or to a related drug is called
A. Drug Tolerance
B. Drug Habituation
C. Drug Addiction
D. Drug Dependence
Answer: A
222. Which one of the following compound is used for the treatment of cyanide poisoning
A. Sodium nitrate
B. Sodium Nitrite
C. Sodium bisulphate
D. Sodium metabisulphate
Answer: B
223. Siam benzoin differs from Sumatra variety due to the insufficient content of
A. Benzoic acid
B. Cinnamic acid
C. Coniferyl alcohol
D. Coniferyl benzoate
Answer: B
224. Glycoside present in the Cinchona bark
A. Quinine
B. Cinchonidine
C. Cinchonin
D. Quinovin
Answer: D
225. Which one of the following is an ingredient of Compound effervescent powder
A. Bismuth subcarbonate
B. Antimony potassium tartarate
C. Sodium potassium tartarate
D. Sodium antimony gluconate
Answer: C
226. Solution containing 6 %w/v of Hydrogen peroxide corresponding to
A. 5 times its volume of available Oxugen
B. 20 times its volume of available Oxugen
C. 10 times its volume of available Oxugen
D. 15 times its volume of available Oxugen
Answer: B
227. Green Vitriol is
A. Ferrous sulphate
B. Zinc sulphate
C. Copper sulphate
D. Magnesium sulphate
Answer: A
228. An agent used for gaseous sterilization
A. Hydrogen sulphide
B. Nitrous oxide
C. Methane
D. Ethylene oxide
Answer: D
229. Which among the following is a substitute of Cinchona
A. Cinchona succirubra
B. Cinchona calisaya
C. Remijia pendunculata
D. Cinchona officinalis
Answer: C
230. Oxytocic activity of the Ergot is due to the presence of
A. Ergotamine
B. Ergometrine
C. Dihydroergotamine
D. Lysergic acid diethylamide
Answer: B